An adipose-derived stem cell has therapeutic applicability. When it comes to regenerating damaged tissues, it has broader applicability. These can be derived through either subcutaneous adipose tissues or liposuction aspirates. From the many clinical trials, adipose has undergone – it has been found to have a broad range of treatment capabilities for various conditions – one reason why such cell therapies are constantly taken under trials of medical research! Let's discuss the benefits stem cells possess.
Stem cells are considered an achievement in the development of modern medicine. The cells have gained popularity in regenerating damaged tissues, capturing medical experts' attention to exploit the benefits these possess. Considering some diseases cause tissues to degenerate, regenerative medicines like stem cells become a healthy way to manage such diseases – especially in place of drugs and surgeries.
Research studies suggest stem cell transplantation is adjusted into the treatment of pain for several diseases. From musculoskeletal pain, neuropathic pain to osteoarthritis – stem cell has proven to help in pain management without having the patients go through complex procedures for treatment and surgeries. In short, stem cell therapies have the potential to repair cartilage in patients having knee osteoarthritis. Research suggests intra-articular injections of stem cells have proven to come up with favorable outcomes – that is, reducing knee-pain and enhancing cartilage quality, and improving physical function. However, intra-articular stem cell therapy doesn't have enough research studies and evidence backing these outcomes.
Adipose tissues are one of the sources of stem cells along with synovial membrane, umbilical cord, and bone-marrow-derived MSCs. Out of these, bone-marrow-derived MSCs are popularly known as the source of adult stem cells to treat knee osteoarthritis. Reason? These easily differentiate into cartilage tissues. Research suggests mesenchymal stem cells have proven to show favorable outcomes in treating knee osteoarthritis. Research has been carried out on this to study the repairing potentials of stem cells. Stem cells derived from synovium and fat pad were considered, including adipose tissue-derived stem cell treated groups and many others in the treatment of OA. This is how the research concluded:
"Treatment of OA with MSCs, particularly synovial membrane-derived stem cells, not only prevented but also healed OA of the knee to some extent in comparison to the Hyalgan and nontreatment groups."
In research conducted to evaluate stem cells' efficacy in OA treatment, MSC derived from adipose tissues and the synovial membrane was considered. The results of the studies showed outcomes in favor of not only synovial membrane but also adipose tissues in reducing the degeneration of the joint cartilage. The research further puts that adipose tissue provides straightforward access to a rich source of MSCs, having the potential to proliferate and differentiate into chondrocytes. In short, the research concluded, the treatment of OA through MSCs derived from adipose tissue and others proved to be effective and useful compared to the others.